Article
Mitochondrial DNA mutations in renal cell carcinomas revealed no general impact on energy metabolism.
British journal of cancer - 30 Jan 2006
Meierhofer D, Mayr J A, Fink K, Schmeller N, Kofler B, Sperl W
Abstract excerpt
Previously, renal cell carcinoma tissues were reported to display a marked reduction of components of the respiratory chain. To elucidate a possible relationship between tumourigenesis and alterations of oxidative phosphorylation, we screened for mutations of the mitochondrial DNA (mtDNA) in rena...
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