Article
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia.
Nature genetics - 30 Oct 2011
Shi Yongyong, Li Zhiqiang, Xu Qi, Wang Ti, Li Tao, Shen Jiawei, Zhang Fengyu, Chen Jianhua, Zhou Guoquan, Ji Weidong, Li Baojie, Xu Yifeng, Liu Dengtang, Wang Peng, Yang Ping, Liu Benxiu, Sun Wensheng, Wan Chunling, Qin Shengying, He Guang, Steinberg Stacy, Cichon Sven, Werge Thomas, Sigurdsson Engilbert, Tosato Sarah, Palotie Aarno, Nöthen Markus M, Rietschel Marcella, Ophoff Roel A, Collier David A, Rujescu Dan, Clair David St, Stefansson Hreinn, Stefansson Kari, Ji Jue, Wang Qingzhong, Li Wenjin, Zheng Linqing, Zhang Hairong, Feng Guoyin, He Lin
Abstract excerpt
Schizophrenia is a severe mental disorder affecting ∼1% of the world population, with heritability of up to 80%. To identify new common genetic risk factors, we performed a genome-wide association study (GWAS) in the Han Chinese population. The discovery sample set consisted of 3,750 individuals with schizophrenia and 6,468 healthy controls (1,578 cases and 1,592 controls from northern Han Chinese, 1,238 cases...
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