Article
A double-blind placebo-controlled study of emtricitabine in chronic hepatitis B.
Archives of internal medicine - 9 Jan 2006
Lim Seng Gee, Ng Tay Meng, Kung Nelson, Krastev Zahary, Volfova Miroslava, Husa Petr, Lee Samuel S, Chan Sing, Shiffman Mitchell L, Washington Mary Kay, Rigney Amy, Anderson Jane, Mondou Elsa, Snow Andrea, Sorbel Jeff, Guan Richard, Rousseau Franck
Abstract excerpt
BACKGROUND: Emtricitabine is a nucleoside analogue approved for treatment of human immunodeficiency virus 1 with clinical activity against hepatitis B virus (HBV). METHODS: To compare the safety and efficacy of emtricitabine with placebo in patients with HBV, we conducted a randomized (2:1), double-blind study at 34 sites in North America, Asia, and Europe that enrolled adults between November 2000 and July 2002...
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