Article
A one-year trial of lamivudine for chronic hepatitis B. Asia Hepatitis Lamivudine Study Group.
The New England journal of medicine - 9 Jul 1998
Lai C L, Chien R N, Leung N W, Chang T T, Guan R, Tai D I, Ng K Y, Wu P C, Dent J C, Barber J, Stephenson S L, Gray D F
Abstract excerpt
BACKGROUND AND METHODS: In preliminary trials, lamivudine, an oral nucleoside analogue, has shown promise for the treatment of chronic hepatitis B. We conducted a one-year, double-blind trial of lamivudine in 358 Chinese patients with chronic hepatitis B. The patients were randomly assigned to re...
Topics
- Adolescent
- Adult
- Aged
- Alanine Transaminase
- DNA, Viral
- Double-Blind Method
- Drug Administration Schedule
- Female
- Hepatitis B e Antigens
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Lamivudine
- Liver
- Liver Cirrhosis