Article
Efficacy of entecavir in chronic hepatitis B patients with persistently normal alanine aminotransferase: randomized, double-blind, placebo-controlled study.
Antiviral therapy - 1 Jan 2014
Tseng Kuo-Chih, Chen Chi-Yi, Tsai Hung-Wen, Chang Ting-Tsung, Chuang Wan-Long, Hsu Ping-I, Liu Wen-Chun, Cheng Pin-Nan
Abstract excerpt
BACKGROUND: It is still inconclusive whether chronic hepatitis B (CHB) patients with persistently normal alanine aminotransferase (PNALT) should receive nucleoside/nucleotide analogues. This study is to evaluate the efficacy of entecavir in improving liver histology in CHB patients with PNALT. METHODS: In this prospective randomized, double-blind, placebo-controlled study, 380 CHB patients with PNALT were...
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