Article
ALL2, a Homologue of ALL1, Has a Distinct Role in Regulating pH Homeostasis in the Pathogen Cryptococcus neoformans.
Infection and immunity - 1 Feb 2016
Jain Neena, Bouklas Tejas, Gupta Anjali, Varshney Avanish K, Orner Erika P, Fries Bettina C
Abstract excerpt
Cryptococcus neoformans is a facultative intracellular fungal pathogen that has a polysaccharide capsule and causes life-threatening meningoencephalitis. Its capsule, as well as its ability to survive in the acidic environment of the phagolysosome, contributes to the pathogen's resilience in the host environment. Previously, we reported that downregulation of allergen 1 (ALL1) results in the secretion of a...
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