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Article

Phenotypical and functional characterization of alveolar macrophage subpopulations in the lungs of NO2-exposed rats.

Respiratory research - 6 Jan 2006

Garn Holger, Siese Anette, Stumpf Sabine, Wensing Anka, Renz Harald, Gemsa Diethard

Abstract excerpt

BACKGROUND: Alveolar macrophages (AM) are known to play an important role in the regulation of inflammatory reactions in the lung, e.g. during the development of chronic lung diseases. Exposure of rats to NO2 has recently been shown to induce a shift in the activation type of AM that is characterized by reduced TNF-alpha and increased IL-10 production. So far it is unclear, whether a functional shift in the...

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Identifiers

PMID: 16398938
DOI: 10.1186/1465-9921-7-4
PMCID: PMC1368986

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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