Article
Growth-dependent modulation of type I collagen production and mRNA levels in cultured human skin fibroblasts.
Biochimica et biophysica acta - 21 Jun 1990
Mäkelä J K, Vuorio T, Vuorio E
Abstract excerpt
Five human skin fibroblast lines were studied for type I collagen production and type I procollagen mRNA levels through the different growth phases. The cells were plated at low density and followed for 11 days at daily intervals through the stages of rapid growth and visual confluency until the...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Northern
- Cell Division
- Cells, Cultured
- Cloning, Molecular
- Collagen
- DNA
- Fibroblasts
- Genetic Variation
- Humans
- In Vitro Techniques
- Molecular Sequence Data
- Mutation
- Plasmids
- RNA, Messenger
- Restriction Mapping
- Sequence Homology, Nucleic Acid