Article
Influence of exogenous growth factors on the expression of plasminogen activators and plasminogen activator inhibitors by cells isolated from normal and healing rabbit ligaments.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jul 1994
Murphy P G, Hart D A
Abstract excerpt
In this investigation, we demonstrate that cells from normal and healing rabbit ligaments are selective in their responsiveness to various growth factors. The cells analyzed included fibroblasts isolated from the synovium, the anterior cruciate ligament, and the medial collateral ligament (midsub...
Topics
- Animals
- Blotting, Northern
- Cells, Cultured
- Culture Media, Conditioned
- DNA
- Dose-Response Relationship, Drug
- Female
- Fibroblast Growth Factor 1
- Fibroblast Growth Factor 2
- Fibroblasts
- Gene Expression Regulation
- Growth Substances
- Insulin-Like Growth Factor I
- Insulin-Like Growth Factor II
- Ligaments
- Phenotype
- Plasminogen Activators
- Plasminogen Inactivators
