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Article

Association of matrilin-3 polymorphisms with spinal disc degeneration and osteoarthritis of the first carpometacarpal joint of the hand.

Annals of the rheumatic diseases - 1 Aug 2006

Min J L, Meulenbelt I, Riyazi N, Kloppenburg M, Houwing-Duistermaat J J, Seymour A B, van Duijn C M, Slagboom P E

Abstract excerpt

BACKGROUND: Seven polymorphisms in the matrilin-3(MATN3) gene were previously tested for genetic association with hand osteoarthritis in an Icelandic cohort. One of the variants, involving a conserved amino acid substitution (T303M; SNP5), was related to idiopathic hand osteoarthritis. OBJECTIVES: To investigate SNP5 and two other promising polymorphisms (rs2242190; SNP3, rs8176070; SNP6) for association with...

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Source

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Identifiers

PMID: 16396979
DOI: 10.1136/ard.2005.045153
PMCID: PMC1798238

Genes

CMC1
MATN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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