Article
Tumor necrosis factor--alpha and transforming growth factor--beta1 polymorphisms in bronchial asthma.
Indian journal of medical sciences - 1 Aug 2008
Kumar Ajay, Gupta Vikas, Changotra Harish, Sarin B C, Sehajpal Prabodh K
Abstract excerpt
BACKGROUND: Bronchial asthma is a complex genetic disorder regulated by the release of cytokines and inflammatory mediators. Tumor necrosis factor alpha (TNF-alpha) and transforming growth factor beta (TGF-beta1) cytokines play pivotal roles in the inflammatory response of the airways. Differential production of these two cytokines is associated with allelic variations in the transcriptional regulatory region of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
