Article
Association of TNF-alpha -308 G/A and IL-4 -589 C/T gene promoter polymorphisms with asthma susceptibility in the south of Iran.
Journal of investigational allergology & clinical immunology - 1 Jan 2007
Kamali-Sarvestani E, Ghayomi M A, Nekoee A
Abstract excerpt
BACKGROUND: Both tumor necrosis factor alpha (TNF-alpha) and interleukin (IL) 4 have been implicated in the pathogenesis of asthma. Furthermore, a G/A substitution at position -308 of the TNF-alpha gene promoter and a C/T substitution at position -589 of the IL-4 gene promoter have been associate...
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