Article
Gene expression profiling of intrinsic thermotolerance in Escherichia coli.
Current microbiology - 1 Jan 2006
Friedman S Marvin, Hossain Mohammed, Hasson Tal H, Kawamura Akira
Abstract excerpt
DNA microarrays were employed to compare gene expression in a thermotolerant, nalidixic acid-resistant mutant of Escherichia coli with that of the parental strain. When grown at 37 degrees C, up-regulated genes in the mutant included those coding for multiple antibiotic resistance proteins and enzymes for the degradation of small molecules, whereas among the down-regulated genes were those coding for fimbrial,...
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