Article
Up-regulation of yggG promotes the survival of Escherichia coli cells containing Era-1 mutant protein.
FEMS microbiology letters - 1 Oct 2007
Huang Yong, Zhang Bin, Dong Ke, Zhang XiaoNan, Hou LiChao, Wang Tao, Chen NanChun, Chen SuMin
Abstract excerpt
Era is a highly conserved GTPase essential for bacterial growth. Using a digoxigenin-labeled Era protein to screen a phage expression library of Escherichia coli genomic DNA, yggG, a gene that encodes a putative zinc metalloprotease was isolated and characterized. The deduced amino acid sequence of YggG showed high degrees of similarity to some reported heat shock proteins. In this study, the direct interaction...
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