Article
Novel phenotypes of Escherichia coli tat mutants revealed by global gene expression and phenotypic analysis.
The Journal of biological chemistry - 12 Nov 2004
Ize Bérengère, Porcelli Ida, Lucchini Sacha, Hinton Jay C, Berks Ben C, Palmer Tracy
Abstract excerpt
The Tat protein export system serves to export folded proteins harboring an N-terminal twin arginine signal peptide across the cytoplasmic membrane. In this study, we have used gene expression profiling of Escherichia coli supported by phenotypic analysis to investigate how cells respond to a defect in the Tat pathway. Previous work has demonstrated that strains mutated in genes encoding essential Tat pathway...
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