Article
Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia.
Archives of general psychiatry - 1 Jan 2006
Peirce Timothy R, Bray Nicholas J, Williams Nigel M, Norton Nadine, Moskvina Valentina, Preece Anna, Haroutunian Vahram, Buxbaum Joseph D, Owen Michael J, O'Donovan Michael C
Abstract excerpt
CONTEXT: Convergent data make 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) a candidate gene for schizophrenia. Reduced expression has been reported in the schizophrenic brain. The CNP gene maps to a region to which we have reported linkage to schizophrenia. Mice in which the CNP gene has been knocked out display central nervous system pathological characteristics reminiscent of some features observed in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
