Article
Changes in pH differently affect the binding properties of histamine H1 receptor antagonists.
European journal of pharmacology - 20 Jan 2006
Gillard Michel, Chatelain Pierre
Abstract excerpt
We investigated the effect of acidic pH, a condition that can be encountered during inflammation accompanying allergic reaction, on the binding properties of histamine H1 receptor antagonists, including levocetirizine ((2-(4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl)ethoxy)acetic acid; X...
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