Article
A single vesicular glutamate transporter is sufficient to fill a synaptic vesicle.
Neuron - 5 Jan 2006
Daniels Richard W, Collins Catherine A, Chen Kaiyun, Gelfand Maria V, Featherstone David E, DiAntonio Aaron
Abstract excerpt
Quantal size is the postsynaptic response to the release of a single synaptic vesicle and is determined in part by the amount of transmitter within that vesicle. At glutamatergic synapses, the vesicular glutamate transporter (VGLUT) fills vesicles with glutamate. While elevated VGLUT expression increases quantal size, the minimum number of transporters required to fill a vesicle is unknown. In Drosophila DVGLUT...
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