Article
Drosophila vesicular monoamine transporter mutants can adapt to reduced or eliminated vesicular stores of dopamine and serotonin.
Genetics - 1 Feb 2009
Simon Anne F, Daniels Richard, Romero-Calderón Rafael, Grygoruk Anna, Chang Hui-Yun, Najibi Rod, Shamouelian David, Salazar Evelyn, Solomon Mordecai, Ackerson Larry C, Maidment Nigel T, Diantonio Aaron, Krantz David E
Abstract excerpt
Physiologic and pathogenic changes in amine release induce dramatic behavioral changes, but the underlying cellular mechanisms remain unclear. To investigate these adaptive processes, we have characterized mutations in the Drosophila vesicular monoamine transporter (dVMAT), which is required for...
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