Article
Synaptic vesicle transporter expression regulates vesicle phenotype and quantal size.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Oct 2000
Pothos E N, Larsen K E, Krantz D E, Liu Y, Haycock J W, Setlik W, Gershon M D, Edwards R H, Sulzer D
Abstract excerpt
While the transporters that accumulate classical neurotransmitters in synaptic vesicles have been identified, little is known about how their expression regulates synaptic transmission. We have used adenoviral-mediated transfection to increase expression of the brain vesicular monoamine transporter VMAT2 and presynaptic amperometric recordings to characterize the effects on quantal release. In presynaptic axonal...
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