Article
Functional and regulatory analysis of the dictyostelium G-box binding factor.
Developmental biology - 15 Jun 2001
Brown J M, Firtel R A
Abstract excerpt
The Dictyostelium discoidium G-box binding factor (GBF) is required for the induction of known postaggregative and cell-type-specific genes. gbf-null cells undergo developmental arrest at the loose-mound stage due to the absence of GBF-targeted gene transcription. GBF-mediated gene expression is activated by stimulation of cell-surface, seven-span cAMP receptors, but this activation is independent of...
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