Article
HLA Class I and II genotype in uveal melanoma: relation to occurrence and prognosis.
Investigative ophthalmology & visual science - 1 Jan 2006
Maat Willem, Haasnoot Geert W, Claas Frans H J, Schalij-Delfos Nicoline E, Schreuder Geziena M T, Jager Martine J
Abstract excerpt
PURPOSE: To assess whether human leukocyte antigen class I and class II alleles confer susceptibility to uveal melanoma or are related to specific clinical or tumor characteristics and survival. METHODS: Between 1990 and 2004, 235 consecutive Dutch patients with diagnoses of primary uveal melanoma were typed for HLA class I and II, either by complement-dependent cytotoxicity test or by DNA-based technique. Allele...
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