Article
HLA-DQB1*0301 association with increased cutaneous melanoma risk.
International journal of cancer - 15 Nov 1994
Lee J E, Reveille J D, Ross M I, Platsoucas C D
Abstract excerpt
Susceptibility to a variety of malignancies has been linked to human leukocyte antigen (HLA) genes, including the HLA class II allele DQB1*0301. To determine whether melanoma risk is associated with HLA class II alleles, molecular oligotyping of HLA class II-DRB1, -DQA1 and -DQB1 genes was perfor...
Topics
- Alleles
- Base Sequence
- Chi-Square Distribution
- DNA Primers
- Female
- Genes, MHC Class II
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans
- Male
- Melanoma
- Molecular Sequence Data
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Risk Factors
- Sex Ratio
- Skin Neoplasms