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Article

The expression of wild-type human amyloid precursor protein affects the dendritic phenotype of neocortical pyramidal neurons in transgenic mice.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Jan 2000

Alpár Alán, Ueberham Uwe, Brückner Martina K, Arendt Thomas, Gärtner Ulrich

Abstract excerpt

The current study addresses the morphoregulatory effects of human amyloid precursor protein expression on neocortical pyramidal cells in vivo. For this purpose, a transgenic mouse line was used that expresses wild-type human amyloid precursor protein (APP) at levels similar to endogenous mouse AP...

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Source

Identifiers

PMID: 16384682
DOI: 10.1016/j.ijdevneu.2005.11.008

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16384682-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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