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Deficiency of SPAG16L Causes Male Infertility Associated with Impaired Sperm Motility1

29 Dec 2005

Abstract excerpt

The axonemes of cilia and flagella contain a "9+2" structure of microtubules and associated proteins. Proteins associated with the central doublet pair have been identified in Chlamydomonas that result in motility defects when mutated. The murine orthologue of the Chlamydomonas PF20 gene, sperm-associated antigen 16 (Spag16), encodes two proteins of M(r) approximately 71 x 10(3) (SPAG16L) and M(r) approximately...

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Identifiers

PMID: 16382026
DOI: 10.1095/biolreprod.105.049254

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Research trail→

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Deficiency of SPAG16L Causes Male Infertility Associated with Impaired Sperm Motility1PMID 16382026Read ↗

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Sperm Antigen 6 Is the Murine Homologue of the Chlamydomonas reinhardtii Central Apparatus Protein Encoded by the PF16 Locus1Semantic proximity Read ↗

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A novel hypomorphic allele of <i>Spag17</i> causes primary ciliary dyskinesia phenotypes in miceSemantic proximity Read ↗

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