Article
[Association study of NOTCH4 gene polymorphisms with schizophrenia and mood disorders in mixed pedigrees].
Yi chuan = Hereditas - 1 Nov 2005
Wang Zuo-Wei, Fang Yi-Ru, Hong Wu, Wang Dong-Xiang, Jing San-Duo
Abstract excerpt
This study was to explore the relationships between NOTCH4 gene and schizophrenia (SP) and mood disorders (MD), and to search for a common susceptible gene for SP and MD in Chinese Han population. We collected 61 mixed pedigrees of SP and MD in Chinese Han population. NOTCH4 polymorphisms -1725T/G and-25T/C were genotyped by applying PCR-RLFP technique, then transmission disequilibrium test (TDT) and...
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