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Article

3'-UTR polymorphism in the human CYP2A6 gene affects mRNA stability and enzyme expression.

Biochemical and biophysical research communications - 10 Feb 2006

Wang Jue, Pitarque Mariá, Ingelman-Sundberg Magnus

Abstract excerpt

Cytochrome P450 2A6 (CYP2A6) is the major nicotine C-oxidase in human and participates in the metabolism of drugs and precarcinogens. The CYP2A6 gene is highly polymorphic and more than 22 different alleles have been described. We here focused on the polymorphism in the 3'-UTR region, in particul...

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PMID: 16378601
DOI: 10.1016/j.bbrc.2005.12.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16378601-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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