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African gene flow to north Brazil as revealed by HBB*S gene haplotype analysis

25 Dec 2005

Abstract excerpt

Haplotypes linked to the HBB*S gene were analyzed in a sample of 260 chromosomes of Brazilian sickle cell anemia patients from the population of Belém, state of Pará, to evaluate if the present-day haplotype frequencies correlate as well as expected with historical information on the geographic origin of African slaves sent directly to Northern Brazil. The HBB*S gene haplotype distribution (66% Bantu, 21.8%...

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PMID: 16378338
DOI: 10.1002/ajhb.20467

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