Importation route of the sickle cell trait into Portugal: contribution of molecular epidemiology.

Article

Importation route of the sickle cell trait into Portugal: contribution of molecular epidemiology.

Human biology - 1 Dec 1992

Lavinha J, Gonçalves J, Faustino P, Romão L, Osório-Almeida L, Peres M J, Picanço I, Martins M C, Ducrocq R, Labie D

Abstract excerpt

To elucidate the origin and spread of the sickle cell trait into the Portuguese population, we examined nine polymorphic DNA markers within the beta globin gene cluster defining the haplotype. The population sample included 64 sickle-cell-gene-bearing individuals from defined Portuguese-speaking...

Topics

Genetics, Population
Haplotypes
Hemoglobin, Sickle
Humans
Models, Genetic
Mutation
Phenotype
Polymerase Chain Reaction
Portugal
Sickle Cell Trait

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