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Article

Incorporating endophenotypes into allele-sharing based linkage tests.

Genetic epidemiology - 1 Feb 2006

Wang Wen-Chang, Chang I-Shou, Chang Chin-Hao, Curb David, Ho Low-Tone, Hsiung Chao A

Abstract excerpt

For a genetic study in which there are concordant and discordant sibpairs for a complex disease trait and the measurements of other endophenotypes/intermediate phenotypes for each of the individuals are also available, we describe an allele-sharing based multipoint linkage test that utilizes nonparametrically the additional endophenotypes/intermediate phenotypes. The usefulness of this method is evaluated in...

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PMID: 16374806
DOI: 10.1002/gepi.20133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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