Article
Variants of the CTLA4 gene that segregate with autoimmune diseases are not associated with endometriosis.
Molecular human reproduction - 1 Oct 2005
Viganó Paola, Lattuada Debora, Somigliana Edgardo, Abbiati Annalisa, Candiani Massimo, Di Blasio Anna Maria
Abstract excerpt
An autoimmune etiology has been suggested for endometriosis mostly on the basis of an increased prevalence of autoimmune diseases in affected women. Cytotoxic T lymphocyte antigen (CTLA) 4 gene is recognized as a primary determinant for autoimmunity since specific polymorphisms have been associated with predisposition to most autoimmune disorders. This study was aimed to evaluate whether two variants of CTLA4...
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