Article
The E-cadherin -160 C/A polymorphism and prostate cancer risk in white and black American men.
The Journal of urology - 1 Aug 2006
Pookot Deepa, Li Long-Cheng, Tabatabai Z Laura, Tanaka Yuichiro, Greene Kirsten L, Dahiya Rajvir
Abstract excerpt
PURPOSE: We have previously reported that a C/A single nucleotide polymorphism at position -160 of the human E-cadherin gene promoter affects E-cadherin transcription. Although this single nucleotide polymorphism is associated with a number of human cancers, including prostate cancer, it is not known whether it has a role in race related prostate cancer. We hypothesized that allelic variation at this site may be...
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