Article
Genetic risk of atherosclerotic renal artery disease: the candidate gene approach in a renal angiography cohort.
Hypertension (Dallas, Tex. : 1979) - 1 Oct 2004
van Onna Marieke, Kroon Abraham A, Houben Alphons J H M, Koster Derk, Zeegers Maurice P A, Henskens Léon H G, Plat Arian W, Stoffers Henri E J H, de Leeuw Peter W
Abstract excerpt
It is largely unknown to what extent genetic abnormalities contribute to the development of atherosclerotic renal artery disease. Among the potential candidate genes, those of the renin-angiotensin system and the endothelial nitric oxide synthase (eNOS) rank high because of their importance in the atherosclerotic process. We investigated the association of polymorphisms in these genes (the angiotensinogen...
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