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Article

Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells.

Cancer research - 15 Dec 2005

Riggi Nicolò, Cironi Luisa, Provero Paolo, Suvà Mario-Luca, Kaloulis Konstantinos, Garcia-Echeverria Carlos, Hoffmann Francesco, Trumpp Andreas, Stamenkovic Ivan

Abstract excerpt

Ewing's sarcoma is a member of Ewing's family tumors (EFTs) and the second most common solid bone and soft tissue malignancy of children and young adults. It is associated in 85% of cases with the t(11;22)(q24:q12) chromosomal translocation that generates fusion of the 5' segment of the EWS gene with the 3' segment of the ETS family gene FLI-1. The EWS-FLI-1 fusion protein behaves as an aberrant transcriptional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16357154
DOI: 10.1158/0008-5472.CAN-05-1696

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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