Article
Ewing sarcoma family of tumors
1 Jul 2000
Abstract excerpt
The Ewing sarcoma family of tumors (ESFT) shares a common neural histogenesis, tumor genetics, and a fascinating biology, all of which hold the promise of identifying new therapeutic targets. The genetic hallmark of ESFT is the presence of the t(11;22)(q24;q12), which creates the EWS/FLI1 fusion gene and results in the expression of a chimeric protein. This article reviews much of the important work that has been...
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