Article
Ewing tumor biology: perspectives for innovative treatment approaches.
Advances in experimental medicine and biology - 1 Jan 2003
Kovar Heinrich
Abstract excerpt
The Ewing's sarcoma family of tumors (EFT) is a group of malignancies affecting bone and soft tissue in adolescents. It is characterized by a unique gene rearrangement between the EWS gene and an ets transcription factor gene. EFT can be cured with conventional multi modal treatment, however, about 40% of patients still succumb to the disease. Relapses can be observed more than 5 years after the end of primary...
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