Article
The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jun 2009
Thoeringer C K, Ripke S, Unschuld P G, Lucae S, Ising M, Bettecken T, Uhr M, Keck M E, Mueller-Myhsok B, Holsboer F, Binder E B, Erhardt A
Abstract excerpt
Recent evidence suggests that the GABA transporter 1 (GAT-1; SLC6A1) plays a role in the pathophysiology and treatment of anxiety disorders. In order to understand the impact of genetic variation within SLC6A1 on pathological anxiety, we performed a case-control association study with anxiety disorder patients with and without syndromal panic attacks. Using the method of sequential addition of cases, we found...
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