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Article

Analysis of interactions with mitochondrial mRNA using mutant forms of yeast NAD(+)-specific isocitrate dehydrogenase.

Biochemistry - 20 Dec 2005

Anderson Sondra L, Lin An-Ping, McAlister-Henn Lee

Abstract excerpt

Yeast NAD(+)-specific isocitrate dehydrogenase (IDH) is an allosterically regulated tricarboxylic acid cycle enzyme that has been shown to bind specifically and with high affinity to 5'-untranslated regions of yeast mitochondrial mRNAs. The absence of IDH has been shown to result in reduced expression of mitochondrial translation products, leading to the suggestion that this macromolecular interaction may...

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Identifiers

PMID: 16342968
DOI: 10.1021/bi0515568
PMCID: PMC2560988

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Source receipt: pubmed, retrieved 7 Sept 2026.

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