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Article

DNA Integrity as a Potential Marker for Stool-based Detection of Colorectal Cancer

1 Jul 2003

Abstract excerpt

BACKGROUND: Molecular genetic analysis of DNA in patient stools has been proposed for screening of colorectal cancer (CRC). Because nonapoptotic cells shed from tumors may contain DNA that is less degraded than DNA fragments from healthy colonic mucosa, our aim was to show that DNA fragments isolated from stools of patients with CRC had higher integrity than DNA isolated from stools of patients with healthy...

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Identifiers

PMID: 12816901
DOI: 10.1373/49.7.1058

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