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Article

Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins.

The EMBO journal - 11 Jan 2006

Wiedemann Nils, Urzica Eugen, Guiard Bernard, Müller Hanne, Lohaus Christiane, Meyer Helmut E, Ryan Michael T, Meisinger Chris, Mühlenhoff Ulrich, Lill Roland, Pfanner Nikolaus

Abstract excerpt

Mitochondria are indispensable for cell viability; however, major mitochondrial functions including citric acid cycle and oxidative phosphorylation are dispensable. Most known essential mitochondrial proteins are involved in preprotein import and assembly, while the only known essential biosynthetic process performed by mitochondria is the biogenesis of iron-sulfur clusters (ISC). The components of the...

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Identifiers

PMID: 16341089
DOI: 10.1038/sj.emboj.7600906
PMCID: PMC1356349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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