Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Iron-sulfur cluster biogenesis and human disease.

Trends in genetics : TIG - 1 Aug 2008

Rouault Tracey A, Tong Wing Hang

Abstract excerpt

Iron-sulfur (Fe-S) clusters are essential for numerous biological processes, including mitochondrial respiratory chain activity and various other enzymatic and regulatory functions. Human Fe-S cluster assembly proteins are frequently encoded by single genes, and inherited defects in some of these genes cause disease. Recently, the spectrum of diseases attributable to abnormal Fe-S cluster biogenesis has extended...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Friedreich Ataxia
Share to Glutaredoxins
Share to Anemia, Sideroblastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP-Binding Cassette Transporters

Share to Frataxin

Share to Iron-Binding Proteins

Share to Iron-Sulfur Proteins

Share to Muscular Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 18606475
DOI: 10.1016/j.tig.2008.05.008
PMCID: PMC2574672

Genes

ISCU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Iron-sulfur cluster biogenesis and human disease.PMID 18606475Read ↗

Iron-sulfur cluster biosynthesis and trafficking - impact on human disease conditions.Semantic proximity Read ↗

Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease.Semantic proximity Read ↗

Mammalian Fe-S cluster biogenesis and its implication in disease.Semantic proximity Read ↗

Iron-sulfur-protein biogenesis in eukaryotes.Semantic proximity Read ↗

Mitochondrial iron-sulfur protein biogenesis and human disease.Semantic proximity Read ↗

Mitochondrial iron-sulfur cluster biogenesis and neurological disorders.Semantic proximity Read ↗

Mammalian mitochondrial iron–sulfur cluster biogenesis and transfer and related human diseasesSemantic proximity Read ↗

[Iron and sulfur in proteins. How does the cell build Fe-S clusters, cofactors essential for life?].Semantic proximity Read ↗

Exome sequencing identifies <i><scp>NFS</scp>1</i> deficiency in a novel Fe‐S cluster disease, infantile mitochondrial complex <scp>II</scp>/<scp>III</scp> deficiencySemantic proximity Read ↗

Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes.Semantic proximity Read ↗

Guardians of the Genome: Iron–Sulfur Proteins in the NucleusSemantic proximity Read ↗

Guardians of the Genome: Iron-Sulfur Proteins in the NucleusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.