Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Mammalian mitochondrial iron–sulfur cluster biogenesis and transfer and related human diseases

1 Jan 2021

Abstract excerpt

As a cofactor, iron-sulfur (Fe-S) cluster binds to proteins or enzymes that play important roles in various important biological processes, including DNA synthesis and repair, mitochondrial function, gene transcription and translation. In mammals, the core components involved in Fe-S cluster biosynthesis are considered to include the scaffold protein ISCU, cysteine desulfurase NFS1 and its accessory proteins...

Topics

Join the communities discussing this publication.

Folate and B Vitamins Research
Metalloenzymes and iron-sulfur proteins
RNA modifications and cancer

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37288145
DOI: 10.52601/bpr.2021.200038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mammalian mitochondrial iron–sulfur cluster biogenesis and transfer and related human diseasesPMID 37288145Read ↗

Iron-sulfur cluster biosynthesis and trafficking - impact on human disease conditions.Semantic proximity Read ↗

Mammalian Fe-S cluster biogenesis and its implication in disease.Semantic proximity Read ↗

Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease.Semantic proximity Read ↗

Iron-sulfur cluster biogenesis and human disease.Semantic proximity Read ↗

Mitochondrial iron-sulfur protein biogenesis and human disease.Semantic proximity Read ↗

Iron-sulfur-protein biogenesis in eukaryotes.Semantic proximity Read ↗

Mitochondrial iron-sulfur cluster biogenesis and neurological disorders.Semantic proximity Read ↗

Guardians of the Genome: Iron–Sulfur Proteins in the NucleusSemantic proximity Read ↗

Guardians of the Genome: Iron-Sulfur Proteins in the NucleusSemantic proximity Read ↗

The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins.Semantic proximity Read ↗

[Iron and sulfur in proteins. How does the cell build Fe-S clusters, cofactors essential for life?].Semantic proximity Read ↗

Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.