Article
The iron-sulphur protein Ind1 is required for effective complex I assembly.
The EMBO journal - 18 Jun 2008
Bych Katrine, Kerscher Stefan, Netz Daili J A, Pierik Antonio J, Zwicker Klaus, Huynen Martijn A, Lill Roland, Brandt Ulrich, Balk Janneke
Abstract excerpt
NADH:ubiquinone oxidoreductase (complex I) of the mitochondrial inner membrane is a multi-subunit protein complex containing eight iron-sulphur (Fe-S) clusters. Little is known about the assembly of complex I and its Fe-S clusters. Here, we report the identification of a mitochondrial protein with a nucleotide-binding domain, named Ind1, that is required specifically for the effective assembly of complex I....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
