Article
Single nucleotide polymorphisms of OCTN1, OCTN2, and DLG5 genes in Greek patients with Crohn's disease.
World journal of gastroenterology - 21 Dec 2005
Gazouli Maria, Mantzaris Gerassimos, Archimandritis Athanassios J, Nasioulas George, Anagnou Nicholas P
Abstract excerpt
AIM: To validate novel single nucleotide polymorphisms (SNPs) in Greek patients with Crohn's disease (CD). METHODS: A total of 120 patients with CD, 85 patients with UC, and 100 unrelated healthy controls were genotyped. Genotyping was performed by allele-specific PCR or by PCR-RFLP analysis. RESULTS: Our results showed that the 1672T and -207C alleles were obviously over-represented in CD patients only (P<0.01...
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