Article
Toll-like receptor 4 in butylated hydroxytoluene-induced mouse pulmonary inflammation and tumorigenesis.
Journal of the National Cancer Institute - 7 Dec 2005
Bauer Alison K, Dixon Darlene, DeGraff Laura M, Cho Hye-Youn, Walker Christopher R, Malkinson Alvin M, Kleeberger Steven R
Abstract excerpt
Because chronic pulmonary diseases predispose to lung neoplasia, the identification of the molecular mechanisms involved could provide novel preventive, diagnostic, and therapeutic strategies. Toll-like receptors (TLRs) transduce exogenous and endogenous signals into the production of inflammator...
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