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Article

Parkin ubiquitinates and promotes the degradation of RanBP2.

The Journal of biological chemistry - 10 Feb 2006

Um Ji Won, Min Do Sik, Rhim Hyewhon, Kim Jongsun, Paik Seung R, Chung Kwang Chul

Abstract excerpt

Parkinson disease (PD) is a common neurodegenerative disorder, which involves the deterioration of dopaminergic neurons in the pars compacta of the substantia nigra. The etiology of PD is still unknown, but recent identification of mutations in familial cases of PD has advanced the understanding of the molecular mechanisms of this neurological disease. Mutations in the parkin gene, which encodes for...

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Identifiers

PMID: 16332688
DOI: 10.1074/jbc.M504994200

Genes

HDAC4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Parkin ubiquitinates and promotes the degradation of RanBP2.PMID 16332688Read ↗

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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligaseSemantic proximity Read ↗

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Parkin: much more than a simple ubiquitin ligase.Semantic proximity Read ↗

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