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Article

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

1 Jul 2000

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Share to Autophagy in Disease and Therapy
Share to Parkinson's Disease Mechanisms and Treatments
Share to Ubiquitin and proteasome pathways

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10888878
DOI: 10.1038/77060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligasePMID 10888878Read ↗

The role of parkin in familial and sporadic Parkinson's disease.Semantic proximity Read ↗

Parkin is linked to the ubiquitin pathwaySemantic proximity Read ↗

Therapeutic potential of Parkin and its regulation in Parkinson's disease.Semantic proximity Read ↗

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Parkin and Parkinsonʼs diseaseSemantic proximity Read ↗

Parkin: a multifaceted ubiquitin ligaseSemantic proximity Read ↗

Parkin ubiquitinates the α-synuclein–interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson diseaseSemantic proximity Read ↗

Parkin functions as an E2-dependent ubiquitin– protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1Semantic proximity Read ↗

Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin‐like domainSemantic proximity Read ↗

Parkin genetics: one model for Parkinson's disease.Semantic proximity Read ↗

Pathologic and therapeutic implications for the cell biology of parkin.Semantic proximity Read ↗

Parkinson's disease-associated protein Parkin: an unusual player in cancer.Semantic proximity Read ↗

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