Article
Serologically defined colon cancer antigen 3 is necessary for the presentation of TNF receptor 1 on cell surface.
DNA and cell biology - 1 Dec 2005
Neznanov Nickolay, Neznanova Lubov, Angres Brigitte, Gudkov Andrei V
Abstract excerpt
Tumor necrosis factor (TNF) induces apoptosis in sensitive cells in culture when used in combination with inhibitors of transcription or translation. We applied the genetic suppressor element (GSE) methodology to search for the genetic elements protecting NIH3T3 cells from TNF-stimulated death. Ten putative GSEs were isolated from TNF-resistant cells, one of which (GSE0-1) corresponded to the cDNA sequence known...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
