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Article

The influence of hepatic lipase C-480T polymorphism on coronary flow reserve in young men is independent of the plasma cholesterol level.

Atherosclerosis - 1 Oct 2006

Fan Yue-Mei, Laaksonen Reijo, Janatuinen Tuula, Vesalainen Risto, Laine Hanna, Raitakari Olli T, Nuutila Pirjo, Knuuti Juhani, Rontu Riikka, Lehtimäki Terho

Abstract excerpt

BACKGROUND: The hepatic lipase (HL) gene C-480T promoter polymorphism affects gene transcription and enzyme activity and leads to CC, CT, and TT genotypes. Recently, HL expression was detected in macrophages. It has been postulated that HL might have a direct role in the pathogenesis of atherosclerosis without changes in the plasma profile. We hypothesized that the difference of plasma cholesterol level may not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16330034
DOI: 10.1016/j.atherosclerosis.2005.11.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The influence of hepatic lipase C-480T polymorphism on coronary flow reserve in young men is independent of the plasma cholesterol level.PMID 16330034Read ↗

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