Article
High-grade transgenic somatic chimeras from chicken embryonic stem cells.
Mechanisms of development - 1 Jan 2006
van de Lavoir Marie-Cecile, Mather-Love Christine, Leighton Philip, Diamond Jennifer H, Heyer Babette S, Roberts Rhys, Zhu Lei, Winters-Digiacinto Peggy, Kerchner Allyn, Gessaro Terri, Swanberg Susan, Delany Mary E, Etches Robert J
Abstract excerpt
Male and female embryonic stem (ES) cell lines were derived from the area pellucidae of Stage X (EG&K) chicken embryos. These ES cell lines were grown in culture for extended periods of time and the majority of the cells retained a diploid karyotype. When reintroduced into Stage VI-X (EG&K) recipient embryos, the cES cells were able to contribute to all somatic tissues. By combining irradiation of the recipient...
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